A therapy parameter-based model for predicting blood glucose concentrations in patients with type 1 diabetes

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A therapy parameter-based model for predicting blood glucose concentrations in patients with type 1 diabetes

In this paper, the problem of predicting blood glucose concentrations (BG) for the treatment of patients with type 1 diabetes, is addressed. Predicting BG is of very high importance as most treatments, which consist in exogenous insulin injections, rely on the availability of BG predictions. Many models that can be used for predicting BG are available in the literature. However, it is widely ad...

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The Challenge of Predicting Future Blood Glucose for Patients with Type I Diabetes

Patients with Type I Diabetes (T1D) must take insulin injections to prevent the serious long term effects of hyperglycemia – high blood glucose (BG). These patients must also be careful not to inject too much insulin because this could induce hypoglycemia (low BG), which can be fatal. Patients therefore follow a “regimen” that, based on various measures, determines how much insulin to inject at...

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Multilevel model of type 1 diabetes mellitus patients for model-based glucose controllers.

BACKGROUND Glucose homeostasis is the result of complex interactions across different biological levels. This multilevel characteristic should be considered when analyzing and designing closed-loop glucose control algorithms. Classic control schemes use only a pharmacokinetic-pharmacodynamic (PKPD) perspective to describe the gluco-regulatory system. METHODS A multilevel model combining a PKP...

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ژورنال

عنوان ژورنال: Computer Methods and Programs in Biomedicine

سال: 2015

ISSN: 0169-2607

DOI: 10.1016/j.cmpb.2014.12.002